Does the P-Shot work for erectile dysfunction?

The research is promising but still early. In a 2021 randomized, placebo-controlled trial of men with mild to moderate ED, more men who received PRP reached a meaningful improvement in erectile function at six months than men who received placebo. A 2023 trial found no significant difference from placebo, and major urology guidelines still consider PRP for ED investigational. We'll tell you honestly whether you're a good candidate, and the P-Shot can sit alongside proven treatments rather than replace them.

Does the P-Shot increase penis size?

There's no reliable clinical evidence that PRP permanently increases penis size, so we don't promise it. Some men notice fuller, firmer erections when erectile function improves. Our focus is function, sensation and comfort, and we'll talk through realistic expectations at your consultation.

How many treatments will I need, and when will I see results?

Most protocols use one to three sessions spaced about four to six weeks apart, depending on your goals and how you respond. Because PRP works through tissue repair, changes tend to build gradually over several weeks to a few months. Your physician will set your plan and check in on your progress.

How much does the P-Shot cost in Toronto?

The P-Shot comes in two options. P-Shot Essential is $900 and uses double-spin PRP in a 30-minute appointment. P-Shot Premium is $1,500 and uses the Arthrex Angel system in a 60-minute appointment. Until January 2027, both are 20% off ($720 and $1,200). Your first call is free, and your physician confirms which option suits you before any treatment. Repeat and multi-session pricing is on our full price list.

Is the P-Shot painful? What are the side effects?

We apply topical numbing first, so most men feel only brief pressure. Because PRP comes from your own blood, allergic reactions are not expected. Mild tenderness, bruising or swelling for a day or two is the most common side effect, and we ask you to avoid sexual activity for about two days afterward.

Can the P-Shot help with Peyronie's disease?

PRP is being studied for Peyronie's disease, the scar tissue that can cause a curve or pain with erections, and early reports are encouraging but limited. If curvature is your main concern, your physician will assess it first and talk you through all your options, including referral to a urologist when that's the better route.

P-Shot in Toronto & Oakville for ED & Peyronie's Disease

Physician-performed PRP injections for men with erectile dysfunction or Peyronie's disease. Every treatment starts with a private physician assessment. Discreet consultations at our Toronto and Oakville clinics, no referral needed.

The P-Shot at Upper Room Clinic

The P-Shot (Priapus Shot) is a platelet-rich plasma (PRP) injection prepared from a small sample of your own blood. Platelets release growth factors involved in tissue repair and new blood vessel formation, and the P-Shot places them directly into the erectile tissue of the penis. Men often explore it when ED medication isn't working well, causes side effects, or isn't the only approach they want.

Erections depend on healthy blood flow, nerves and hormones, so ED can be an early sign of something else, like heart disease, diabetes or low testosterone. That's why every P-Shot at Upper Room starts with a physician looking at the whole picture.

Physician-assessed. Your candidacy is confirmed before any treatment
Discreet. Private consultations in Toronto and Oakville
Efficient. One 30 to 60 minute visit with topical numbing
Transparent pricing. $900 for Essential, $1,500 for Premium

Is the P-Shot Right For You?

The P-Shot is for men who want to improve erectile function or address Peyronie's disease, especially when standard treatments haven't been enough. It's often considered for:

Mild to moderate erectile dysfunction
ED medication that isn't working well or causes side effects
Peyronie's disease, including curvature or pain with erections
Weaker erections or reduced sensitivity with age
Men who want a regenerative option alongside root-cause care

Medication, lifestyle changes and other proven treatments remain first-line options for ED. If the P-Shot isn't the right fit for you, we'll tell you.

Couple's hands reaching together against a blue sky — intimacy and connection

Man sprinting on a track — restored energy and performance

The Benefits

Because the P-Shot uses your own blood, it offers a regenerative option with a short visit and little downtime.

Your own biology. PRP is prepared from your blood, so allergic reactions are not expected
No daily medication. Treatment happens in a short series of visits
Minimally invasive. Topical numbing and a fine needle, with no surgery
Little downtime. Most men return to normal activities the same day
Whole-person care. We look at hormones, circulation and metabolic health too

Results vary from person to person, and your physician will talk through realistic expectations before you decide.

What to Expect

Consultation

Before Treatment

Treatment

After Care

Every P-Shot starts with a private consultation. Your physician reviews your sexual health concerns, medical history and medications, may order bloodwork such as testosterone or blood sugar, and confirms whether the P-Shot is right for you. If it is, we'll recommend Essential or Premium and talk through realistic outcomes.

Drink plenty of water in the days leading up to your appointment. Stop nicotine and alcohol at least 24 hours beforehand, and eat a meal at least 2 hours before your treatment.

We draw a small amount of blood and concentrate the platelets, which takes about 15 minutes for Essential or 30 to 45 minutes on the Arthrex Angel system for Premium. Topical numbing is applied, then your physician performs the injection. Plan for about 30 minutes for Essential or 60 minutes for Premium.

Mild tenderness for a day or two is normal. Avoid sex or masturbation for at least 2 days, and avoid NSAIDs (like Advil), recreational drugs and alcohol for at least 5 days after your injection. You'll go home with a vacuum device and instructions from our team on how to use it as part of your aftercare.

During Treatment

A P-Shot Essential appointment takes about 30 minutes and a Premium appointment about 60 minutes, most of which is preparing your PRP. With topical numbing, most men feel only brief pressure during the injection. Expect mild tenderness for about two days and avoid sexual activity during that time. Any changes tend to build gradually over the following weeks to months.

Why Choose Upper Room Clinic

P-Shot treatments at Upper Room Clinic are assessed and performed by our physicians, led by Dr. Biljana Kostovic, who brings over 30 years of clinical experience across Emergency Medicine, Pain Medicine and integrative care.

A physician assesses every patient before treatment
Two PRP preparation options, including the Arthrex Angel system, which concentrates platelets up to 18× baseline
A functional medicine approach that looks at hormones, circulation and metabolic health
Private, discreet care at our Toronto and Oakville clinics

We'll give you a straight answer about whether the P-Shot is likely to help, and what else might.

Arthrex Angel PRP system used to prepare platelet-rich plasma at Upper Room Clinic

P-Shot Pricing in Toronto & Oakville

Two ways to get your P-Shot, with transparent pricing at both locations. Your discovery call is free, and a physician confirms your candidacy and protocol before any treatment.

Limited-time pricing

20% off both P-Shot options

Available until January 2027.

Essential

P-Shot Essential

$900 $720

Our streamlined P-Shot. PRP is prepared with a double-spin centrifugation process, so the whole visit fits into a shorter appointment.

Appointment: about 30 minutes
PRP prepared by double-spin centrifugation in about 15 minutes
Topical numbing and a physician-performed injection
Well suited to ED support, maintenance, or trying the P-Shot for the first time

Choose Essential

Premium

P-Shot Premium

$1,500 $1,200

Our highest-concentration P-Shot. Your blood is processed on the Arthrex Angel® system for up to 18× baseline platelet concentration, maximizing what each injection delivers.

Appointment: about 60 minutes
PRP processed on the Arthrex Angel® system for 30–45 minutes
Topical numbing and a physician-performed injection
Recommended for Peyronie's support and multi-session protocols

Choose Premium

Not sure which is right for you? Your physician will confirm your candidacy and recommend the best option during your consultation.

Thank you. A member of our team will call you privately to answer your questions and book your consultation.

Something went wrong sending your request. Please try again, or call our Davisville clinic at 647-521-8024.

Repeat treatments and multi-session pricing are listed on our full Services & Diagnostic Testing price list, or ask during your call.

Frequently Asked Questions

Dive into our learning portal and expand your knowledge base.

Learn More

The P-Shot for Men: How It Works and Who It Helps

The P-Shot for ED: how PRP works, what current mixed clinical evidence shows, and key facts to know before treatment.

Medically reviewed by Dr. Biljana Kostovic, MD — Medical Director, Upper Room Clinic. Last updated August 2026.

Selected references

Epifanova MV, Gvasalia BR, Durashov MA, Artemenko SA. Platelet-Rich Plasma Therapy for Male Sexual Dysfunction: Myth or Reality? Sex Med Rev. 2020;8(1):106–113.

Israeli JM, Lokeshwar SD, Efimenko IV, Masterson TA, Ramasamy R. The potential of platelet-rich plasma injections and stem cell therapy for penile rejuvenation. Int J Impot Res. 2022;34(4):375–382.

Poulios E, Mykoniatis I, Pyrgidis N, et al. Platelet-Rich Plasma (PRP) Improves Erectile Function: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. J Sex Med. 2021;18(5):926–935.

Masterson TA, Molina M, Ibrahim E, Ramasamy R. Platelet-rich Plasma for the Treatment of Erectile Dysfunction: A Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial. J Urol. 2023;210(1):154–161.

Individual results vary and no outcome is guaranteed. The P-Shot is not appropriate for every patient — a physician assessment is required to determine whether it is right for you.

Locations
Upper Room Clinic – Oakville
Tel: 647-521-8024 ext. 2
Fax: (289) 644-0255
oakville@upperroomclinic.com

Upper Room Clinic – Davisville
Tel: 647-521-8024
Fax: 647-348-8024
hello@upperroomclinic.com

Tuesday to Saturday
11am-6pm

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