Vitamin B12 is what your body uses to build red blood cells, insulate nerves, and run the methylation reactions behind energy and mood. It is absorbed in the last stretch of the small intestine, and getting it there needs stomach acid and a protein called intrinsic factor. When any link in that chain breaks, oral B12 stops being reliable no matter how large the tablet — which is why an injection is often the more dependable route. Every shot at Upper Room Clinic, at both our Toronto and Oakville locations, is given by clinical staff under physician oversight.
B12 deficiency creeps in slowly and gets blamed on stress, age, or a busy life. Fatigue that sleep does not fix, brain fog, pins and needles in the hands or feet, a sore tongue, low mood. Long-term metformin, proton pump inhibitors and H2 blockers all deplete it — and the risk compounds when they are taken together. So do bariatric surgery, bowel resection, celiac disease, Crohn's, and a fully plant-based diet without reliable supplementation. A simple blood test is all it takes to find out where you stand.
MTHFR is the enzyme that makes the active folate your body needs to run methylation. The common C677T variant reduces that enzyme's activity, which raises homocysteine. It is common: roughly four in ten people carry one copy, and around one in ten carry two.
Cyanocobalamin, the cheap synthetic form used by most walk-in clinics and in food fortification, carries a small cyanide group the body has to remove. It occurs in human tissue only in trace amounts. Methylcobalamin, adenosylcobalamin and hydroxocobalamin are the natural forms found in the body and in food, and a 2017 review of B12 forms favoured those natural forms over cyanocobalamin for bioavailability and safety. The same review notes that some genetic variants can affect how well a person absorbs and processes B12.
We use methylcobalamin at both locations. If you already know your MTHFR status, tell us when you book. If you do not and you would like to, we can arrange the genetic testing that identifies variants affecting methylation.
A B12 injection is for people whose levels are low, or whose absorption makes low levels likely. Common reasons our patients book one include:
Because an injection bypasses the gut, it does what tablets often cannot — deliver a known dose, reliably, regardless of how well you absorb.
Book directly — no referral and no prescription needed. You get portal access when you book, so upload any recent bloodwork and we will match your dose to your measured level rather than estimating it. There is nothing to prepare and no need to fast. If you already know your MTHFR status, tell us at this stage.
Methylcobalamin is injected into the muscle of the upper arm by our clinical staff, under physician oversight. The injection itself takes moments, and most people are in and out well inside fifteen minutes.
You can drive yourself home and go straight back to your day. Some people notice more energy within days; where levels were genuinely low, the fuller benefit builds over several weeks as your body makes new red blood cells and nerve symptoms settle.
$60 for the 5,000 mcg correction dose and $40 for the 1,000 mcg maintenance dose, or five for $270 and $180. Most people run a short course at a set interval rather than a single shot. Where it is useful we recheck your level, step you down to maintenance, and send results to your family doctor.
B12 therapy at Upper Room Clinic is overseen by Dr. Biljana Kostovic, a physician with over 30 years of clinical experience spanning emergency medicine, pain medicine and integrative care. That matters more than it sounds. Fatigue, brain fog and neuropathy have a long list of possible causes, and a clinic that can only sell you a shot will sell you a shot. We can requisition the bloodwork, read it in context, and tell you when B12 is not the answer.
With locations in Davisville, Toronto and Oakville, you do not need a referral to be seen — though it is highly beneficial to share your family doctor's information with us, so we can coordinate bloodwork, share your results, and keep your GP in the loop. Book directly for a straightforward shot, or start with a wellness intake if you want the dose and interval matched to your measured level — in a monitored, physician-led medical clinic rather than a walk-in drip lounge.
Contact Us
Locations
Upper Room Clinic – Oakville
Tel: 647-521-8024 ext. 2
Fax: (289) 644-0255
oakville@upperroomclinic.com
Upper Room Clinic – Davisville
Tel: 647-521-8024
Fax: 647-348-8024
hello@upperroomclinic.com
Tuesday to Saturday
11am-6pm
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